When Monroe Blackwell, who is spending the summer at her grandmother's Louisiana bed-and-breakfast, meets Nathan Everets, who has a court-appointed job there, they share, and begin to recover from, their respective feelings of loss and guilt.

High school senior Liz, a gifted photographer, can no longer see things clearly after her best friend accuses Liz's older brother of a terrible crime.

To honor her dead boyfriend and cope with her grief and guilt, college student Annie trains for a marathon with athletic Jeremiah, who flirts with Annie on the trails and makes her feel alive and happy and guilty all at the same time.

Penny feels guilty after taking a beautiful blue marble that she sees in Mrs. Goodwin's grass, but gets a pleasant surprise when she goes to return it the next day.

Traumatized by grief and guilt after her younger brother dies during a family vacation, fifteen-year-old Shiv is sent away to an exclusive clinic that claims to "cure" people like her.

After coming out of alcohol rehabilitation, sixteen-year-old Amy sorts out conflicting emotions about her best friend Julia's death in a car accident for which she feels responsible.

Mathilda (Tilly), fourteen, and Ruth Anne (Roo), sixteen, are sisters and best friends in Connecticut, but when Roo crashes her car while texting she is confined to a hospital bed with "locked-in syndrome," aware of her surroundings, but apparently comatose--and Tilly must find a way to communicate with her sister, while dealing with her own sense of guilt.

When Jake is involved in a street-racing accident, he struggles to do the right thing. Jake lucha para tomar la decisión correcta después de ser involucrado en un accidente.

After being acquitted of murder, seventeen-year-old David goes to stay with relatives in Cambridge, Massachusetts, where he finds himself forced to face his past as he learns more about his strange young cousin Lily.

Fifteen-year-old Lizzie Cohen recalls what it was like growing up with her imaginative but disturbed older sister Tess, and how she is striving to reclaim her own life since Tess died.