Beezus' biggest problem was her 4-year-old sister Ramona. Even though Beezus knew sisters were supposed to love each other, with a sister like Ramona, it seemed impossible.

Ramona's year in third grade is highlighted by the arrival of Howie's rich Uncle Hobart, a change in her after-school situation, a surprise wedding, a death and a new arrival in the family, and her father's getting a job.